The Pennsylvania Department of Transportation, abbreviated as PennDOT, owns 39,861 miles (64,150 km) of the 121,770 miles (195,970 km) of roadway in the state, making it the fifth largest state highway system in the United States. The Pennsylvania Turnpike system is 535 miles (861 km) long, with the mainline portion stretching from Ohio to Philadelphia and New Jersey. It is overseen by the Pennsylvania Turnpike Commission. Another major east–west route is Interstate 80, whichs runs primarily in the northern tier of the state from Ohio to New Jersey at the Delaware Water Gap. Interstate 90 travels the relatively short distance between Ohio and New York through Erie County, in the extreme northwestern part of the state.
Primary north–south highways are Interstate 79 from its terminus in Erie through Pittsburgh to West Virginia, Interstate 81 from New York through Scranton, Lackawanna County and Harrisburg to Maryland and Interstate 476, which begins 7 miles (11 km) north of the Delaware border, in Chester, Delaware County and travels 132 miles (212 km) to Clarks Summit, Lackawanna County, where it joins I-81. All but 20 miles (32 km) of I-476 is the Northeast Extension of the Pennsylvania Turnpike, while the highway south of the main line of the Pennsylvania Turnpike is officially called the "Veterans Memorial Highway", but is commonly referred to by locals as the "Blue Route".
The Southeastern Pennsylvania Transportation Authority (SEPTA) is the sixth largest transit agency in the United States and operates the commuter, heavy and light rail transit, and transit bus service in the Philadelphia metropolitan area. The Port Authority of Allegheny County is the 25th largest transit agency and provides transit bus and light rail service in and around Pittsburgh.
Intercity passenger rail transit is provided by Amtrak, with the majority of traffic occurring on the Keystone Service in the high-speed Keystone Corridor between Harrisburg and Philadelphia's 30th Street Station before heading north to New York City; the Pennsylvanian follows the same route from New York City to Harrisburg, but extends out to Pittsburgh. The Capitol Limited also passes through Pittsburgh, as well as Connellsville, on its way from Chicago to Washington, D.C. Traveling between Chicago and New York City, the Lake Shore Limited passes through Erie once in each direction. There are 67 short-line, freight railroads operating in Pennsylvania, the highest number in any U.S. state.
Pennsylvania has six major airports: Philadelphia International, Pittsburgh International, Lehigh Valley International, Harrisburg International, Erie International, and Wilkes-Barre/Scranton International. A total of 134 public-use airport are located in the state. The port of Pittsburgh is the second largest inland port in the United States and the 18th largest port overall; the Port of Philadelphia is the 24th largest port in the United States. Pennsylvania's only port on the Great Lakes is located in Erie.
The Allegheny River Lock and Dam Two is the most-used lock operated by the United States Army Corps of Engineers of its 255 nationwide. The dam impounds the Allegheny River near Downtown Pittsburgh.